Phenylpropanoids and polyketides
TARGETMOL CHEMICALS INC --GALLOCATECHIN 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (-)-Gallocatechin ((−)-GC) has free radical scavenging ability and moderate affinity to the human cannabinoid receptor. purity: 99%
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | 98.0% | 170.17 g/mol | C10H6N2O | 5 MG
Tyrphostin 8 is a small-molecule tyrosine kinase inhibitor supplied for research use. It inhibits EGFR kinase (IC50 = 560 μM), acts as a GTPase inhibitor, and inhibits calcineurin (IC50 = 21 μM). The compound is provided as a high-purity solid and is available in small-mass vials or as a DMSO solution for in vitro biochemical and cell-based assays.
- High purity (>98%), suitable for in vitro studies.
- Known activity against EGFR, GTPase, and calcineurin targets.
- Molecular weight 170.17 g/mol and formula C10H6N2O.
- Available in multiple small pack sizes and as a 10 mM DMSO solution.
- Light yellow to yellow solid for handling and storage.
TARGETMOL CHEMICALS INC ML-090 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2 NOX3 NOX4 (all IC50s >10 uM). purity: 98%
Medchemexpress LLC Xanthohumol | 6754-58-1 | 354.40 | 1 ML
Xanthohumol is a principal flavonoid derived from hops, acting as an inhibitor of diacylglycerol acyltransferase (DGAT), COX-1, and COX-2. It exhibits anti-cancer and anti-angiogenic properties. Additionally, Xanthohumol demonstrates antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
- Inhibits diacylglycerol acyltransferase (DGAT), COX-1, and COX-2.
- Shows anti-cancer activities.
- Shows anti-angiogenic activities.
- Has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
Medchemexpress LLC Apigenin (4',5,7-Trihydroxyflavone) | 520-36-5 | 270.24 | 5 G
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM. This natural flavonoid possesses broad biological properties including antioxidative, anti-inflammatory, anticancer, and neuroprotective effects.
- Competitive CYP2C9 inhibitor
- Exhibits antioxidative effects
- Exhibits anti-inflammatory effects
- Exhibits anticancer effects
- Exhibits neuroprotective effects
- Inhibits cell proliferation
- Alleviates Adriamycin (ADR)-induced myocardial injury
Medchemexpress LLC (-)-Catechin | 18829-70-4 | 290.27 | 1 ML
(-)-Catechin is a structural isomer of Catechin. It inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. Additionally, (-)-Catechin promotes the differentiation of hBM-MSC adipose cells, leading to increased fat cell differentiation and PPARγ levels. It is intended for research use only.
- Inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
- Promotes adipocyte differentiation in human bone marrow mesenchymal stem cells (hBM-MSC).
- Increases fat cell differentiation.
- Increases PPARγ level.
Medchemexpress LLC Xanthohumol D | 274675-25-1 | 370.40 | 5 MG
Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with an IC50 value of 110 μM, and binds to the active site of QR-2. It shows antiproliferative activity on human cancer cell lines in vitro.
- Inhibitor of quinone reductase-2 (QR-2) with an IC50 value of 110 μM
- Binds to the active site of QR-2
- Exhibits antiproliferative activity on human cancer cell lines in vitro
Medchemexpress LLC Apigenin (Standard) | 520-36-5 | 270.24 | 5 MG
Apigenin (Standard) is the analytical standard of Apigenin, intended for research and analytical applications. It is a competitive CYP2C9 inhibitor with a Ki of 2 μM. This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS. Features and benefits include:
- Purity: 98.82%
- Appearance: solid
- Color: yellow to brown
- Structure classification: flavonoids, phenols
- Initial source: plants Compositae Baccharis sarothroides A.Gray, plants Umbelliferae
- Endogenous metabolite: human gut microbiota metabolites
Medchemexpress LLC Benzoin (DL-Benzoin) | 119-53-9 | 100.0% | 100 G
Benzoin (DL-Benzoin) is a PI3Kα inhibitor that exhibits anticancer effects. It has been shown to inhibit the growth of the colon cancer cell line (HCT-116) with an IC50 of 2.12 mM. This product is for research use only and not sold to patients. Its chemical formula is C14H12O2, and it has a molecular weight of 212.25. It appears as a white to off-white solid.
- Exhibits anticancer effects.
- Inhibits the growth of colon cancer cell line (HCT-116).
- White to off-white solid appearance.
- Chemical formula C14H12O2.
- Molecular weight 212.25.
TARGETMOL CHEMICALS INC QUERCETAGETIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Quercetagetin (6-Hydroxyquercetin) (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50 0.34 uM). purity: 99%
Medchemexpress LLC Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) | 132465-11-3 | 99.41% | 321.33 | 50 MG
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) is a potent inhibitor of 12/15-Lipoxygenases (LO) with potential for type 1 diabetes mellitus research. In vitro studies demonstrated that CDC partially suppressed dextran transport, while in vivo, it antagonized the effect of high glucose on protein phosphorylation, mitigating endothelial cell barrier destruction in a mouse diabetes mellitus model.
- Potent 12/15-Lipoxygenases (LO) inhibitor
- Potential for research of type 1 diabetes mellitus
- Partially suppressed dextran transport increased by high glucose or 12(S)-HETE in vitro
- Antagonized the effect of high glucose on protein phosphorylation in vivo
- Mitigated endothelial cell barrier destruction in a mouse diabetes mellitus model
TARGETMOL CHEMICALS INC NOBILETIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). purity: 98%
TARGETMOL CHEMICALS INC METRONIDAZOLE BENZOATE 100MG
Also available in and bulk. Please contact Fisher for quotes. Metronidazole Benzoate (Benzoyl metronidazole) is a derivative of Metronidazole and benzoic acid which has antibacterial anti-parasitic and anti-trichomonas functions and is often used to treat infections caused by anaerobic bacteria. Metronidazole Benzoate is a salt form of Metronidazole an antibiotic compound commonly used to treat bacterial and parasitic infections. purity: 99%
Medchemexpress LLC p-Hydroxycinnamic acid | 7400-08-0 | 10 G
p-Hydroxycinnamic acid is a chemical compound (CAS No. 7400-08-0) primarily utilized as a laboratory chemical and in the manufacture of other substances. With a molecular formula of C9H8O3 and a molecular weight of 164.16, this white to off-white solid is stable under recommended storage conditions and is intended for research use only.
- Appears as a white to off-white solid
- Purity of 99.94% by HPLC
- Structure consistent with ¹H NMR spectrum
- Stable under recommended storage conditions
- Melting point ranges from 212-214°C
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 2 years or -20°C for 1 year
- Requires careful handling to avoid skin, eye, and respiratory irritation
Medchemexpress LLC Nicotiflorin | 17650-84-9 | 594.52 | 1 ML
Nicotiflorin is a flavonoid glycoside extracted from the traditional Chinese medicine *Carthamus tinctorius*. It exhibits potent antiglycation activity and neuroprotection effects.
- Flavonoid glycoside
- Extracted from Carthamus tinctorius
- Potent antiglycation activity
- Neuroprotection effects
- Attenuates cell death and reduces LDH release in cultured neurons
- Increases eNOS activity, mRNA, and protein levels in cultured rat cerebral blood vessel endothelial cells
- Reduces brain infarct volume and neurological deficits in rats following cerebral ischemia